->"This spell allows me to exploit the petty prejudices of man. Minor grievance would escalate to murderous rage and oh, the sweet terror when the spell wore off and they saw their hands covered with their neighbor's blood."
--> -- Kain, Blood Omen, LegacyOfKain
A plot wherein the characters are affected by a force unknown to them and become increasingly snappish and disagreeable to each other, sometimes escalating to outright murderousness. This is often a subtle plan by the Villain of the show who figures it's easier to let the heroes kill off each other. Naturally, the heroes realize it just in time. This is sometimes a way for characters to vent hitherto unmentioned grievances. Ironically, despite the use of AppliedPhlebotinum, this is a more believable version of ToiletSeatDivorce and ConflictBall, since everyone is NotHimself.
The TropeNamer is the plot of the TransformersGeneration1 cartoon storyline "The Return of Optimus Prime", a red glowy virus transmitted by touch that affects human and robot alike. Contrast with LoveIsInTheAir. Subtrope of EmotionBomb. See also MindVirus and ArtifactOfAttraction. In video games with StandardStatusEffects, this can show up as an actual game mechanic, usually "Confusion" or "Berserk."
folder:Anime and Manga
* VisualNovel/HigurashiNoNakuKoroNi arguably DeconstructedTrope deconstructs this trope spoiler:since the main characters always suffer from it. Through most of the arcs, no one figures it out, and as a result, anywhere from more than half of to the entire cast winds up dead at the various ends.
** HigurashiNoNakuKoroNiKai turns it straight again when spoiler:the heroes learn about the plague in question and conquer it with ThePowerOfTrust.
** Further, one character does have it figured out in every arc (and a few more know about it but don't find out about specific instances until too late). spoiler:Unfortunately, by not fighting against it aggressively enough she produces the same effect as if she hadn't known about it at all, which is to say none, and still gets to watch her friends descend into violent madness.
** It's actually more of a spoiler:Paranoia Plague than a HatePlague, with a side order of spoiler:hallucination, but it gets the job done.
* In Anime/ReadOrDie The Television Series, one VillainOfTheWeek uses two kinds of sounds to protect his base as the heroines try to infiltrate it, both of them out of the range of normal hearing: one is a subsonic hum that enhances depression and melancholy in people who are already disposed to it, and the other is a supersonic hum that makes more excitable people angrier and more irritable.
* Yubel uses this in duels to great effect in YuGiOhGX Yu-Gi-Oh! GX. While she's on the field as a monster, she can force monsters to attack her; she takes no battle damage, and inflicts the same damage to her opponent in retribution. She calls this effect "Nightmare Pain." Shortly after Yubel reveals herself in Season 3, Judai's cloest friends are also infected with a Hate Plague against him, which was quite effective in bringing out his SuperpoweredEvilSide, especially when followed by their apparent deaths.
* In the first Star Trek manga, a man and a woman who were once lovers (and who had a bit of a falling out) come on board the ship. They end up making all the men and women on board turn against each other merely from their presence.
* Also Transformers-related, one issue of Marvel's Generation2 comics featured black energy goo beings that induced and lived on other creatures' aggression.
* Inverted in the ComicBook/Hellblazer arc "The Red Right Hand", in which the plague makes its victims incredibly empathic. Unfortunately it takes hold in ViolentGlaswegian Glasgow and so everyone begins to share one another's guilt and misery, culminating in mass suicides.
* An alternate version of the New XMen, set in the House of M universe, dealt with Wallflower, a mutant with pheromone powers, causing Sooraya to engulf her best friend Jubilee in a sandstorm that likely would have shredded her body to its bones if given time.
* In TheSavageDragon #55, a massively powerful mind-controller PowerIncontinence unintentionally sends everyone in Chicago into a murderous rage the moment he steps out of his bunker.
* In a Series/StarTrekTheOriginalSeries comic a long time ago (it came with a vinyl record to read along with) wherein an alien Cat Girl's pet, a Waul, gets loose on the Enterprise. It's agitated yowling makes everyone on the crew start sniping at each other, and the closer they got to the critter the worse it got. Once it was reunited with its mistress, it was happy and purring again.
* During the BlackestNight, EmotionEater Psycho-Pirate used these on Smallville. NightmareFuel ensued as his mask's abilities to influence any nearby target to near-suicidal hatred, uncontrollable fear or demented avarice ensued, heightening minor feelings to killing urges.
* The main shtick of the villain Hate-Monger from the MarvelUniverse. (Who is actually AdolfHitler. )
** And Psycho-Man, a FantasticFour villain.
** A new (non-Hitler) Hate Monger appears in a Punisher story as the leader of a racist organization. The Punisher infiltrates the group, but discovers that his final initiation is to beat a Hispanic reporter investigating the group to death. Unfortunately, by then he's succumbed to the Hate Monger's HatePlague and he goes through with it. Doubly unfortunately she was the girlfriend of the Punisher's current tech guy. Needless to say, there was a falling out and a rare bout of guilt for Frank Castle.
* In Asterix and the Roman Agent, Tortuous Convolvulus has the ability to sow mistrust (indicated by SpeechBubbles gaining a green background) that quickly escalates into shouting and fistfights.
** He complemented the power of causing mistrust and discord by his presence alone (he didn't have to say or do a thing to start a fight between Caesar's advisers) with a good amount of mundane skill in psychological warfare and sowing mistrust and fear. He also had been sentenced to death at the Colosseum, and was alive at the beginning of the book due to CrowningMomentOfAwesome making the beasts attack one another.
* In JudgeDredd East Meg One used a literal Rage Virus as a precursor to invading Mega City One.
* In ArchieComics, a flower putting off purple "bad vibe lines" caused nearby people to start acting meanly and selfishly. It, naturally, got passed around town for a while during the course of the story, making as many people as possible get into shouting matches. Probably not the only time such a story happened in that series.
* The eponymous BlackGas of Warren Ellis' ZombieApocalypse -style comic operates via progressive brain damage, eating away at the parts of the brain responsible for people's inhibitions.
* The WonderWoman villainess Genocide has powerful energy blasts. Anyone lucky enough to survive the explosion gets consumed by rage and paranoia.
** Ares tends to incite rage in order to start wars.
* Batman: Jekyll and Hyde had a drug that was described as unifying the conflicting halves of a person's identity. Apparently everyone secretly wants to murder, torture, and/or cannibalize the nearest primate. Huh.
* Les Schtroumpfs Noirs (The Black TheSmurfs Smurfs), the first Smurf comic book story, involved a Smurf being bit by a blackfly. As a result of the bite, the Smurf turned solid black and became insane, spreading the plague by biting his fellow Smurfs' tails. Fortunately Papa Smurf was able to cure the plague before it was too late. This story was made into an episode of the Smurfs cartoon, although in the cartoon, the evil Smurfs were [[Bowdlerise purple, not black]].
* In AstroCity, when Black Velvet is mortally wounded by Jitterjack, her body releases black energy that infects the populace and starts a riot.
* In the earlier ComicBook/SonicTheHedgehog comics, evil wizard Ixis Naugus can amplify peoples' emotions. This is hinted to be the driving point for the Great War between the Mobians and human-esque Overlanders, and then the Mobian/Robian civil war.
** More recently, he used that same magic on the citizens of New Mobotropolis, magnifying their mistrust of NICOLE - following her stint being BrainwashedAndCrazy brainwashed by the Iron Dominion - into full-blown paranoia, so that they will view her as a threat, and him as their "DarkMessiah savior".
* The plot of ComicBook/Template:Crossed is centered on a virus that causes its victims to turn into predatory psychopaths.
* In ComicBook/DarkwingDuck, the Phantom Blot has created an inky mind-altering substance to create new rogues in St. Canard which is also used to control the populace briefly.
folder:Films -- Live-Action
* TwentyEightDaysLater 28 Days Later and its sequel revolve around a TechnicallyLivingZombie sort of ZombieApocalypse caused by a literal Hate ThePlague Plague, the Rage Virus.
** Ditto TheCrazies and Template:REC. TheCrazies is a somewhat different variant, as the infected often retain coherence and elements of their personality, unlike the mindless fury of the 28 movies and Template:REC.
* In the movie Return in Red, a government agency uses sound waves to induce insanity and homicidal urges in the people of a small town.
* In the movie Ghostbusters II, the sewers of New York City become filled with an ectoplasmic sludge that absorbs emotions. The Ghostbusters discover it while it's been negatively charged, and after they end up covered in it, they briefly end up going at each other's throats. Egon discovers the malleable nature of the slime, however, and in order to break through a barrier of negatively-charged slime, the Ghostbusters positively charge some of it through CrowningMomentOfAwesome a combination of the song "Higher and Higher", and the most inspiring thing they can find in Manhattan: The Statue of Liberty.
* One of the "non-lethal" weapons employed by the good guys at the end of MysteryMen is a ray (the Blame Thrower) that can cause angry arguments amongst whomever gets hit with it. A rare case of the protagonists employing such a tactic as psychological warfare.
* Film/Serenity: The Reavers (murdering, raping madmen who terrorize the fringes of the strike:universe small star cluster/ solar system) are revealed to be [[spoiler:the victims of a government-sponsored lotus-drug gone so bad. It was meant to weed out aggression in the population. Instead it made the majority of the population so passive that they couldn't even be bothered to take basic measures to continue living, while it became a Hate Plague for a fraction of a percent of the population. They proceeded to wipe out whoever was left, and then start recruiting.]]
* This is the alien threat in the film Film/AlienCargo.
* Utilized by Loki through his scepter in Film/TheAvengers to make the already volatile team turn on each other so as to distract them from his assault and unleash the TheIncredibleHulk Hulk upon S.H.I.E.L.D.'s helicarrier.
* The Cunning Man from Discworld/IShallWearMidnight is an embodiment of this. He's the ghost of a witch hunter whose hatred for witches is so great, wherever he goes people become more suspicious and angry with witches.
* In David Moody's Template:Hater and its sequel DogBlood, a virus causes people to murder their loved ones and anyone else in their path. The local media even calls the infected people "haters."
* Played with in StarTrekATimeTo. It sort of happens on the planet Delta Sigma IV, in A Time to Love and A Time to Hate, only with a twist. [[spoiler: The plague isn't really causing the hate and violence- in fact, it's curing the populace of a mind-altering drug that kept them peaceful. Suddenly confronting emotions such as hate and rage for the first time, the Delta Sigma inhabitants can't cope, and old racial tensions erupt into violence. Riots soon spread across the planet.]]
* Used in DavidEddings' TheElenium Elenium arc--the negative influence of the MacGuffin / SealedEvilInACan, the Bhelliom, causes the heroic FiveManBand to start getting mutinous...
** The Bhelliom got far nicer in the Tamuli, though.
* HarryPotter, in Deathly Hallows spoiler:the Slytherin Locket Horcrux has this effect and leads to Ron leaving the group for a while.
* TheChroniclesOfAncientDarkness have a few hate plague-inducing things, including the Fire Opal and soul-sickness.
* In James Tiptree Jr.'s short story "The Screwfly Solution", a mysterious plague spreads outward from the equator, turning male sexual urges into murderous violence against women.
* In Template:Cell (the 2006 horror novel by Stephen King) a signal (possibly sent by terrorists) broadcast over cell phones strips away the higher functions of the brain, leaving just a state of murderous rage. spoiler:The infected then progressively evolve into an organized, non-raged Hive Mind and develop psychic powers.
** Another StephenKing example, 1987 novel TheTommyknockers. A crashed spaceship begins to effect the area around it, causing the inhabitants of the nearby town of Haven to start changing, mentally and physically. During the mid-point of their transformation, they begin seeking out and killing those who have done them wrong, regardless of whether that wrong was real or simply perceived. spoiler:The residents of Haven then progressively evolve into an organized, non-raged HiveMind and develop psychic powers. Hmm . . . y'know, that sounds familiar.
** Steven King also used the idea in NeedfulThings, where the BigBad, Mr Gaunt (a demon, if not the devil himself) manipulates the town into destroying itself through a series of escalating "pranks". Evidently Mr King likes this trope.
* The novel One Rainy Night by Richard Laymon is about a bizarre black rain that causes AxCrazy Ax Craziness in everyone who gets wet.
** Similarly, the Brian Keene short story "Purple Reign" features purple rain that does the same, though this HatePlague affects animals as well as humans.
* In The Long Last Call by John Skipp, the Devil goes to a strip club, where his tainted fifty dollar bills inspire murderous rage in the employees. Yes, even the girls. Especially the girls.
* The One Ring in TheLordOfTheRings has this effect, turning people against one another by playing on their lust to use its power, particularly on Bilbo and Boromir. Was shown well in the film adaptation in a shot which showed the arguing Council of Elrond reflected in the Ring as fire blazed within.
** Also the flashback to Deágol and Sméagol finding the Ring while fishing. Within minutes Sméagol (Gollum) has killed his relative in order to possess the Ring.
** Sam proved resistant when he used it to rescue Frodo, since he had no desire for power whatsoever.
** spoiler: Faramir was also resistant. Well, in the original text, anyway.
*** Even in their cases it still took a fair bit of willpower.
*** spoiler: Boromir was exposed to the ring far longer than his brother; Tolkien may portray one as a "better" man, but FridgeLogic the younger brother had been exposed for only hours, not days and days.
*** spoiler: Boromir showed hints of being tempted during the council scene, immediately upon being faced with the ring.
*** [[spoiler: The Ring works on ambition as well as hate. Faramir just wanted to live his life, and if he happened to be some sort of hero it would only be because he had to. Boromir wanted to be a big famous hero, cast down Mordor, restore Gondor and Arnor to their former glory. Certainly not a bad ambition, but the Ring can latch on to that to start its HatePlague after taking hold.]]
** Morgoth in TheSilmarillion was capable of sending these off with his will eventually, although he was just as good at using rumor and misdirection to accomplish the same end without sorcery.
* AbleTeam Able Team #8: Army of Devils. A drug capable of creating instant rage in the user is smuggled into Los Angeles, in an attempt to create a race war in the United States.
* One of the Dinotopia companion novels (The Maze) includes a heavier-than-air HatePlague-inducing gas as one of the obstacles en route to the center of the titular maze. [[spoiler: The raptor of the trio is driven out of the group first and decides to go up the walls, clearing his head. He then manages to take advantage of the gas' effects to dare the other two to stay together and not kill each other until they get out of the hazard zone.]]
* In Literature/TheWheelOfTime, the dagger from Shadar Logoth is so tainted with evil that his carrier becomes paranoid and hateful, and then starts to infect other people.
** Padan Fain, a recurring villain partially possessed by the spirit who created Shadar Logoth, also has this effect- people who spend too much time in his company become increasingly paranoid, ill-tempered, and generally corrupt. When he gets the dagger back (another character carries it for a good chunk of the early books) his powers are increased dramatically.
* Kyr Bulychev's book The Purple Sphere is about an artificial virus (stored in the titular container) which causes unnatural hatred in anyone infected. The developers got infected. They killed each other off, the rest of their planet's biosphere evolved into a Template:Deathworld.
* JamesHerbertsTheFog is about the titular mist--it's SealedEvilInACan a bio-weapon that turns half of England insane and depraved in a manner very reminiscent of TheCrazies.
** The Dark by the same author uses a more supernatural version of the same trope, with similar results.
* The god of war Ares in PercyJacksonAndTheOlympians radiates an aura that makes people around him more susceptible to violent impulses. It's not quite a weapon, but it means the characters have to be more careful around him since he is always looking for an excuse to start a fight.
* Brian Keene's Jack's Magic Beans takes place in the same universe as the aforementioned "Purple Reign", but this time, the HatePlague has no detectable cause and doesn't appear to affect animals or people who take Prozac.
* StarTrekTheOriginalSeries, "Day of the Dove": An Template:Energy Being that feeds on hate brings the Federation and the Klingons, who are trying to abide by the peace treaty, into conflict. It goes as far as implanting FalseMemories so that the manipulated will have an extra source of conflict. An interesting part of this trope in Star Trek is that those who are killed are somehow brought back to life with their fatal wounds healed to fight again. Once they all figure it out the creature is repelled from the ship by laughter. Lots and lots of laughter.
** In "The Tholian Web," a NegativeSpaceWedgie drove the crew of one starship to kill each other, and then begins to drive the Enterprise crew to outbursts of anger.
** In "This Side Of Paradise", an anger-inducing sonic broadcast is used to counteract the effects of tranquility-inducing spores.
* StarTrekTheNextGeneration also had such an episode, which was caused by an aging Vulcan telepathically "leaking" his suppressed emotions into the minds of the crew. [[spoiler: Said aged Vulcan is Spock's father, and he has, basically, Vulcan Alzheimer's Disease. Picard puts his mind at risk by letting him "absorb" some of his willpower because if anyone finds out, the treaty Spock's dad has been working on for years, if not decades could be at risk. By the by, the effects on Picard really gave his actor, Patrick Stewart, a chance to shine.]]
* StarTrekEnterprise had an episode where the closer the ship got to an undetected NegativeSpaceWedgie singularity, the more the crew started to freak out, basically giving them a nuclear version of SuperOCD.
** This is also one of the possible effects of GreenSkinnedSpaceBabe Orion pheromones on other women.
* Series/Template:Crusade, the sequel to Series/Babylon 5, had an episode where the crew visited a planet that was boobytrapped with a means of driving visitors into murderous rages.
** It was much more devious. The people would not only perform violent acts. Afterwards, they would have no memory of the event and instead remember seeing a shadowy figure performing the act. Of course, it wasn't really a plague but spoiler:Technomage nanites.
* The Croatoan virus from Series/Supernatural, which was later part of HorsemenOfTheApocalypse Pestilence's plan to release it nationwide as part of [[Satan Lucifer's]] endgame.
* Not quite a hate plague but a spiritual sister to the trope would be the depression toxin from the Series/RedDwarf episode "Back To Reality".
* Used for humorous effect in the "Syzygy" episode of TheXFiles, in which a rare planetary alignment causes strange behavior in a small town, and even Mulder and Scully begin to snipe at each other.
** More serious versions appear in "Ice" in which an extraterrestrial parasite causes an Arctic research team, and later the investigating team, to turn on each other by increasing their paranoia; and in "Red Museum" as part of a GovernmentConspiracy the children of a town are infected with alien DNA which causes an increase in violent behaviour.
* Series/Angel had a variant: the touch of a particular vicious misogynist caused any man he touched to hate and attack any woman they came near.
** In another episode, the bizarreness of the week causes people to bleed from their eyes and go into a murderous rage about whatever they feel.
* One episode of The 4400 concerned an attack by a 4400 who was able to stimulate aggression in men, resulting in a breakdown of discipline at NTAC headquarters.
* The Hate Master, one of the many MonstersOfTheWeek that the PowerRangers had to deal with, has this as its primary ability.
* An early episode of Stargate SG-1 subjected the team to hypersonic frequencies that made some of them very irritable, resulting in a shouting match and a delightfully awkward non-apology apology afterward.
** A minor one was caused by withdrawal symptoms from some creepy Goa'uld light in the episode with the same name. Similarly, Daniel's withdrawal from the sarcophagus in Need had him almost shooting Jack in one scene.
* Series/TheSarahJaneAdventures had a single-target variation, where anyone who heard or read the name "Clyde Langer" turned against Clyde.
* An episode ('Sense and Antisense") of Series/Millennium (the TV series produced by Chris Carter) has Frank Black tracking down a man supposedly infected by a hate virus. At the end we see a photograph of the man posing with military personnel marked "Kigali, Rwanda, 1994".
* An episode of TheManFromUncle The Man from U.N.C.L.E. ('The Suburbia Affair') centered around a plot like this-- the electric lights in a suburban neighborhood vibrated on a frequency that caused the people living there, including our undercover heroes, to become irritable, suffer headaches, and fight amongst themselves. A mob scene was narrowly averted at the town meeting.
* The Series/Farscape episode "Crackers Don't Matter" has a highly amusing Hate Plague, causing several characters to become obsessed with ensuring their fair share of crackers, to the point of barricades and gun battles.
* One of the Gelliant Gutfright sketches from ABitOfFryAndLaurie features the "Fighting Buttercup," a flower which causes anger and aggression spoiler: for about five minutes. And then explodes.
* Eureka - "All the Rage": A device designed to calm people down GoneHorriblyWrong instead turns GD into ShoutOut "a Romero NightOfTheLivingDead movie".
* UltraSeven episode 8 had aliens lace cigarettes with a toxic seed that made humans violent. It was all a plan to repopulate the Earth after humans wiped each other out.
* In Series/Template:Alphas, one of the VillainsOfTheWeek Matthew Hurly has the ability to release pheromones that causes the people around him explode in homicidal rage.
* The "Hound of Baskerville", in the Series/Sherlock episode of that name, turns out to have been a hallucinogenic drug that also functioned as this, giving those it was forced upon images of horrible monsters... and then making them want to murder them.
* Dracorage in ForgottenRealms was murderous madness periodically magically induced in dragons world-wide. Designed by ancient elves to break dragons' control over the world, later magical device was hijacked and used [[spoiler:by Sammaster to convince evil dragons that becoming Template:Undead with his help is their only option to avoid insanity and then ignominious death.]]
* Mindflayers are given magical stones that could potentially have this result in the DungeonsAndDragons D&D 3.5 supplement Lords of Madness.
* TabletopGame/PrometheanTheCreated has Disquiet, an instinctual reaction by all living things towards the titular creatures that makes them gradually desire to destroy them-even if that isn't normally in a person's nature (several times, the book features humans going into HumansAreBastards jerk-mode towards Prometheans, MyGodWhatHaveIDone then wondering exactly why they were doing that a moment later). Is it any wonder that a Prommie's quest ToBecomeHuman BlessedWithSuck makes perfect sense?\\
There are two things that don't instinctively hate Prometheans -- Vampires and Werewolves. Instead, they find Prometheans so unsettling that it actually becomes harder for them to resist their UnstoppableRage -- meaning that they'll quite likely end up killing the Promethean anyway, along with any other allies or innocents that are unfortunate enough to be there at the time.
* One of the horrors described in the GURPS sourcebook Creatures of the Night is the Dread Blossom, a flower that makes people exposed to its scent paranoid and xenophobic.
* Wraiths in TabletopGame/Shadowrun can cause uncontrollable aggression in those near them.
* Skarbrand in WarHammer and WarHammer40000 has a special rule which causes EVERYONE around him to reroll misses in close combat due to amplifies hate.
* Some Apostates in BlackCrusade can 'Inspire Wrath' in people against specific targets, with just a few words. It makes PlayerCharacters more determined, and so more likely to, hit the subjects. [=NPCs=] are a little less predictable.
* Classic Traveller Adventure 6 Leviathan. When the PC's explore the world Pa'an, the natives will use their psionic powers to inflict telepathically induced aggression toward other party members. The crew will begin by feeling antagonistic and short-tempered with each other, and within one to six hours will be actively engaged in trying to finish each other off.
* VillainsAndVigilantes adventure Devil's Domain. When the PC's are fighting at the Stonehenge tower, killing a demon will cause it to explode in a cloud of demon ichor, which becomes a toxic brown smoke. After the battle is over, if the PC's didn't destroy the smoke when it was created it will cause inhabitants of the nearby town to converge on Stonehenge in a killing frenzy directed at anyone who isn't infected.
* In BIONICLE, the Dreaming Plague's first symptoms included irritability, which then grew to hatred and violent behaviour, finally leading to complete insanity followed by death.
** This is one way Kurahk can use its power.
* Video game example (sort of): in Nethack, there is a "ring of conflict" that, when worn, makes every creature (including peaceful creatures and the player's own pets) start attacking the player and each other.
* In Postal 2, [[spoiler:when you complete all of your tasks on Friday, you suddenly get a newspaper highlighting how a Hate Plague has instantly affected the whole town. Now you have to make it back home amidst the chaos, which includes raining dervish cats. At least everyone's usually focused on killing each other instead of you in particular.]]
* In Blood Omen: LegacyOfKain, the player can generate this effect with the 'Inspire Hate' spell, causing all nearby Mooks to ignore the player and attack each other. The description of the spell specifically states Kain's sadistic amusement with the effect this has on the survivors...
** Kain gains the same ability in Defiance. In both cases it's related to the CosmicKeystone pillar of conflict.
* This is the main goal of Dr. Regal in MegaManBattleNetwork 5: Combine the Soul Net (unifying all hearts) with the power of the Dark Chip (makes people evil). We see a little bit of the effects during the cutscene before the FinalBoss.
** Gemini Spark's chapter's evil plan in MegaManStarForce is to attach a virtual plus or minus to each person, invariably attaching the same sign to two friends, lovers, spouses, etc. so that they'd argue with each other. The game never explored the effect of two people with opposite signs...
** It's pulled again at the end of the second game. The villain gets away with it for a while, too, and this time without the awkward positive/negative questions.
*** The BonusDungeon of the same game is a twisted BadFuture in which the villan's plan actually succeeded and humanity was completely wiped out. The result is a rather depressing dungeon where you wander around a world without life or hope, and kill insane versions of your allies from the normal time line and eventually confront a BonusBoss who's sole intention is to escape to your world and wreak havoc on it as well.
* The infectious "kombat rage" spreading from OriginalGeneration Dark Kahn's mere existence in MortalKombatVsDCUniverse is a straight example, though this is also subverted when Superman and Raiden eventually realize that they can focus their rage towards what they see as the invaders rather than each other. During gameplay, it also serves as a literally UnstoppableRage.
* In the video game Template:Majesty: The Fantasy Kingdom Sim, one temple provides the spell "Rage of Krolm" which promptly fills your heroes with an unstoppable rage that gives them bonuses to fighting ability.
* The violence of Condemned centers on this.
* Used in spell form in SuikodenIII, during the attack on spoiler:Karaya Village, which results in Chris killing Hugo's friend Lulu, and Boris going berserk on unarmed civilians. Naturally, the bad guys did this to sour relations between the Grasslanders and the Zexens, so as to be able to conquer them both later on without any troubles.
* Used in CommandAndConquer 3: Kane's Wrath. The Brotherhood of Nod's HumongousMecha the Redeemer can cause enemy units to go into a rage; attacking anything within sight (including their allies); but only after they finish off their current target first.
** Black Hand Confessors in the same game can throw hallucinogenic grenades, which cause any infantry caught in their area of effect (including friendlies) to attack their own allies. Unfortunately, it doesn't affect vehicles.
** Similarly, in RedAlert 2: Yuri's Revenge, Yuri's faction has the Chaos Drone, which emits MushroomSamba a psychedelic gas with a similar effect. Or to be more exact, the gas causes units affected by it to prioritize targeting friendlies over targeting foes, with an UnstoppableRage extra helping of doubled rate of fire.
* Fallout 3 has Vault 108, a social experiment where the interior was pumped full of hallucinogenic gases to see how the inhabitants would react. Result: everyone had gone insane and killed each other.
** Vault 92 as well. Using the internal PA system, everyone was subjected to low-frequency white noise with combat suggestions hidden in it. After a while, everyone who heard it gone berserk and brutally killed the nearest person.
* Left4Dead doesn't actually feature the undead, but rather "infected" humans, in the vein of 28 Days Later, which WordOfGod the developers cite as an inspiration.
* ResidentEvil has this introduced instead of the zombie plague in all the other games in the form of Las Plagas, which (in their normal form) are only able to make their victims more aggressive, albeit controlled. Experiments show how much BodyHorror worse this can actually be for its victims.
* In TraumaTeam, almost all of the murders solved by Naomi was caused by the murderer being infected with the spoiler:Rosalia virus.
** Though it isn't straight up hate, but rather a result of frontal lobe tumors causing dementia. At least one murderer though she was trying to save her family from a FateWorseThanDeath.
* In Bioshock, the Enrage plasmid causes splicers to go crazy (well, crazier than usual) and attack anyone-- you, their fellow splicers, or even Big Daddies.
* This happens in VideoGame/PokemonColosseum and its sequel Pokémon XD. Pokemon's hearts are closed, so that they have no sense of compassion, and only their primal bloodlust. They'll attack anything, and they sometimes go into uncontrollable rage fits.
* The Pox of [=LeChuck=] in TalesOfMonkeyIsland.
* The Delphinius Parasite in Franchise/ShinMegamiTensei: StrangeJourney is effectively this, though they have difficulty even finding out a physical vector for the disease.
** ParanoiaFuel Because it does EnergyBeings not have one.
* Features in DeadlyPremonition. spoiler:A purple gas produced from the Red Seeds that drives people into a murderous rage was responsible for the Original Raincoat Killer incident.
** And it happens again spoiler: during the last mission of the game. Killing the FinalBoss puts a stop to it though.
* KingdomOfLoathing: Almost everything that increases monster leveling has a description to that effect. The Annoy-o-Tron, the badly tuned radio, the Canadian Mind Control Device which takes it UpToEleven... even, as a ShoutOut to Nethack, a ring of conflict. Most infamous is the hockey stick of furious angry rage, which is imbued with everything that makes hockey hockey.
* One of Omega's powers in MegaManZero is his ability to turn normally sane reploids into murderous psychopaths. This power combined with his bloodthirsty desire to kill is ultimately what caused the deaths of 90% of reploids and 60% of humans in the Elf Wars. Imagine a robotic Skarbrand and you have Omega in a nutshell.
* The ChekhovsGun Spice from SlyCooper 2 causes insanity and unbound hatred, the BigBad spoiler: Constaple Neyla/Clockla intends to use this worldwide hatred to fuel spoiler: her immortality.
* According to most Touhou fanon, this is how GreenEyedMonster Parsee's "power of jealousy" works. Well, that and BulletHell...
* The TropeNamer is the Hate Plague in TransformersGeneration1. Also occurred as one of a small handful of Shout Outs in WesternAnimation/BeastMachines.
** Despite the name, it doesn't really fit. The infected often initially become violent, but will then begin to work together with other infected. In the second of the two-parter that introduced the plague, Cyclonus commands the other Decepticons to retreat after coming under fire from the Autobots, and they follow his orders unquestioningly. It's more of a "Lack of inhibitions" plague than a "hate" plague.
*** One example of the afflicted cooperating are the combiners. In spite of fighting amongst themselves minutes earlier, the Aerialbots re-combine into Superion. They later infect Defensor. Defensor immediately collapses into the 5 Protectobots; the five fight amongst themselves. The same happens when Galvatron raids the lab containing the plague. Menasor and Bruticus are touched immediately by afflicted Autobots and immediately collapse into 10 brawling Transformers.
*** The Decepticons' cooperation could be FridgeBrilliance at work, as hatred had already been a part of their driving motivation, so wouldn't necessarily alter their behavior as much as it does, the non-villainous characters'. Doubly so for Menasor and the Stunticons, whose bios indicate that they operate on a level that barely makes it up to TeethClenchedTeamwork.
* In JusticeLeague, supervillain Gorilla Grodd uses his mental abilities to give the team's minor issues with each other a little push, much to their embarrassment.
* Both the Film/TheCareBearsMovie first and Film/CareBearsMovieIIANewGeneration second CareBears movies show the villains having a dark influence on surrounding people - the kids at the amusement park where Nicholas and the evil book are become rotten little monsters, and so do the kids at the camp where Dark Heart sets up shop.
** One episode of the animated series featured a AppliedPhlebotinum mysterious meteorite infecting a small town, making the surroundings dull and gray and the citizens depressed and apathetic. NightmareFuel/CareBears Rather creepy, FridgeHorror in retrospect, when it started affecting the Care Bears as well.
* The SoBadItsGood Template:Batfink program featured main recurring villain Hugo A-Go-Go creating "hoke", a combination of hate and smoke. After it was released, the eponymous hero and his sidekick began arguing, including LampshadeHanging placing a lampshade on the overuse of the hero's "LuckilyMyPowersWillProtectMe My wings of steel will protect me" catchphrase, with the henchman replying, "Yeah, yeah, why don't you get some new dialogue?"
* An episode of PowerpuffGirls had [[Satan Him]] replace everyone's love with hate, causing them to turn against the girls - even the Narrator was affected.
** Really hit home when the girls went to see the Professor. Imagine all the love a parent has for their children magically swapped with hate.
* A more family friendly version is see in TheodoreTugboat, in the debut episode of Guysborough the Garbage barge. His grumpiness gets Theodore in a bad mood, which puts Emily & George in a bad mood and so on until the entire harbour becomes snappy with each other.
* One episode of WesternAnimation/DungeonsAndDragons, featuring the usual "get to the one-chance exit back home" set-up, forced the kids to go through a maze to reach a portal. One part of the maze made all the kids become very aggressive, tetchy and downright bloodthirsty, which almost resulted in a nasty fight. Fortunately, Hank was able to snap everyone out of it.
* The MyLittlePony MyLittlePonyTheMovie movie had the Smooze, which, in addition to making everything putrid and covering the land in a thick layer of concrete-like substance, made characters touched by it aggressive, spiteful and pessimistic.
* WesternAnimation/MyLittlePonyFriendshipIsMagic: In Recap/MyLittlePonyFriendshipIsMagicS2E1TheReturnOfHarmonyPart1 "The Return of Harmony", Discord inflicts most of the main characters with the opposite emotions from their respective PersonalityPowers Elements of Harmony. Honest Applejack becomes a liar, merry Pinkie Pie becomes serious and irritable, generous Rarity becomes greedy, kind Fluttershy becomes cruel and loyal Rainbow Dash deserts her friends.
* The little pink dog CourageTheCowardlyDog Courage once faced a literal sweeping Hate Plague called the "Cruelty Curtain". This energy barrier caused anyone it touched to become ridiculously rude to the point where benevolence was considered a crime. Courage managed to re-wire the Curtain so that it turned people nice--HeelFaceTurn even its evil creator, who was later elected mayor.
folder:Alternate Reality Games
* The Red Horse virus in the NineInchNails Year Zero ARG is a weaponised haemorrhagic virus that causes violent psychosis, encouraging the spread of a disease that would otherwise be self-limiting given its extreme virulence.
* Mob mentality can often resemble this.
** Historically, the Mob mentality revolving around Witch Trials seen in Salem, Massachusetts are said to have been amplified by a disease caused by a certain type of mold that worked its way into the people's grain, making this example a little more literal.
* In the right doses, the right drugs can induce a psychotic episode, which can lead to explosively violent outbursts. However, the victim is just as likely to pass out, have a heart attack, or go on a bad acid trip instead, so the effect can't be used reliably as a weapon.
* Many illnesses, such as rabies or brain tumors, often result in mood swings and sometimes increased aggressiveness.
* Dogs (particularly in Springer Spaniels) can have something called "Rage Syndrome" which does resemble Hate Plague. Fortunately, it's rare and it only lasts a few minutes.